About this trial
Comparative efficacy of topical 1% clotrimazole vs oral itraconazole in the treatment of pityriasis versicolor -Randomized control trial
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age (15-50 years)
Both genders
Sufferers of Pityriasis versicolor ( Determined by scale , erythema and pruritus)
Disqualifiers
Pt with history of antifungals in last one month
Pt on immunosuppressants or steroid therapy
Pregnant and lactating women
Pt with chronic medical conditions ( Diabetes and hypertension)
Trial design
Parallel
Treatments tested in this trial
Topical 1 % clotrimazole twice daily 2 weeks
DrugTopical 1% clotrimazole twice daily for 2 weeks
Oral itraconazole 200mg daily for 5 days
DrugOral itraconazole 200mg daily for 5 days
Treatment groups
Trial outcomes
Primary outcomes
Percentile efficacy of topical versus oral antifungal in the treatment of pityriasis versicolor
Data analysis will be performed using SPSS version 20. The quantitative variable (age, BMI and duration of PV) will be presented as mean ± standard deviation (SD) or median interquartile range (IQR) after checking normality of data by using Shapiro-Wilk test. Frequency and percentages will be used for categorical variables (gender, severity of PV, area of residence, level of education and efficacy). Efficacy will be compared between groups using Chi-square or Fisher exact test. Efficacy will be stratified by age, gender, BMI, duration of PV and severity of PV to deal with effect modifiers. Post-stratification chi-square test or Fischer exact test will be used as test of significance. A p-value of ≤ 0.05 will be considered statistically significant.
Locations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options: