Comparison of Efficacy of Betamethasone Gel With Lidocaine Gel in Prevention of Post Endotracheal Intubation Sore Throat.

ConditionPost Operative Sore Throat at 6hrs and 24hrs After Endotracheal Intubation

Trial statusNot yet recruiting

Trial phasePhase 1, Phase 2

Trial typeInterventional

Biological sexAll

Age18-60

SponsorJinnah Postgraduate Medical Centre

About this trial

The goal of this clinical trial is to compare the incidence of postoperative sore throat in adult patients of either gender belonging to ASA I or II ,undergoing endotracheal intubation using betamethasone gel versus lidocaine gel. It aims to determine

1: Difference in efficacy of Betamethasone gel and lidocaine gel in prevention of post operative sore throat after endotracheal intubation.

Patients will be assessed for the presence of a sore throat at 6 hours and 24 hours postoperatively. The severity of the sore throat will be graded using the Post-Operative Sore Throat (POST) score.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Patients aged 18-60 years

Either gender

ASA I to II

Patients planned for elective surgery under general anesthesia not lasting more than 4 hours.

Disqualifiers

Patients requiring more than 2 attempts for successful intubation

Patients undergoing surgeries of oral cavity or pharynx

Mallampati Score of 3 or 4

Patients with upper respiratory tract infection

Trial design

Design model

Parallel

Treatments tested in this trial

Betamethasone dipropionate 0.05%
Drug
It is corticosteroid indicated for relief of inflammatory and pruritic manifestation
Lidocaine hydrochloride 2%
Drug
It is amide local anesthetic used for lubrication and pain prevention as topical anesthetic regimen

Treatment groups

60 Participants

are divided into 2 treatment groups

Group A: Group A receiving betamethasone gel during endotracheal intubationActive comparator 1 intervention

Group B: Group B receiving lidocaine gel during endotracheal intubationActive comparator 1 intervention

Trial outcomes

Primary outcomes

Post operative sore throat

Comparing presence and grading of sore throat in both arms after endotracheal intubation.

Time frame

Sore throat after endotracheal intubation at 6 hrs and 24hrs post operatively. Sample completion in 2 weeks

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Jinnah Postgraduate Medical Centre

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: