Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's Palsy
ConditionBell Palsy
Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18-60
SponsorOctober 6 University
About this trial
Bell's palsy, a peripheral facial nerve paresis, is the most common disorder of the facial nerve and one of the most common mononeuropathies.
Many patients with Bell's palsy will develop some complications such as synkinesis, crocodile tears and 'sweating' of the ear while eating Commonly used medications to treat Bell's palsy is Corticosteroids Cerebrolysin stimulates the regeneration of the nervous tissue with protective action we aim to study the efficacy of cerebrolycin in Bell's palsy
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
unilateral acute facial palsy of no identifiable cause
Disqualifiers
Recurrent facial Bell's palsy
Pregnancy
Diabetes
Epilepsy
Trial design
Design model
Parallel
Treatments tested in this trial
Prednisolone
Drugprednisolone 60mg tablet once daily for 5 days then tapering dose
Cerebrolysin
Drugintramuscular Cerebrolysin 10 mg daily for 3 weeks
Treatment groups
90 Participants
are divided into 3 treatment groupsGroup A: PrednisoloneActive comparator 1 intervention
Group B: CerebrolysinActive comparator 1 intervention
Group C: Prednisolone and CerebrolysinActive comparator 2 interventions
Trial outcomes
Primary outcomes
1
change in scores of the house Brackman grading system HB
Time frame
at baseline, after 1 week, after 3 week2
changes in scores of the Sunnybrook grading system.
Time frame
at baseline, after 1 week, after 3 weekSponsors and contacts
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Source ClinicalTrials.gov