Empirical Radioactive Iodine Therapy in DTC
ConditionDifferentiated Thyroid Cancer
Trial statusNot yet recruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssiut University
About this trial
The aim of the study is assessment the efficacy of empiric RAI therapy in DTC patients with elevated thyroglobulin levels and negative iodine scintigraphy.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
This study will include adult patients with pathologically proved DTC who underwent total thyroidectomy and received RAI therapy presented to our nuclear medicine unit with evidence of persistent or recurrent biochemical disease during follow up.
Disqualifiers
Undifferentiated thyroid cancer.
Patients with evidence of structural disease.
Patients less than 18 years old.
Trial design
Design model
Parallel
Treatments tested in this trial
Radioactive Iodine Therapy
Drugempirical dose of RAI
Treatment groups
100 Participants
are divided into 2 treatment groupsGroup A: patients received empirical dose of RAIExperimental treatment 1 intervention
Group B: patients didn't receive empirical dose of RAINo intervention 0 interventions
Trial outcomes
Primary outcomes
1
efficacy of empirical radioactive iodine therapy
by assessment of tumor marker (serum thyroglobulin ) if decreased after empirical therapy
Time frame
2 yearsLocations
Sponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: