Erector Spinae Plane Block with Dexmedetomidine and Bupivacain Versus Dexamethasone and Bupivacain for Postoperative Analgesia in Patients Undergoing Abdominal Surgeries

Trial statusNot yet recruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18-65
SponsorLoay Gamal

About this trial

To compare the analgesic effect of dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Patient refusal

known sensitivity or contraindication to any of study drugs

contraindications for local anesthesia

Patients with local infection at site of puncture

Trial design

Design model

Parallel

Treatments tested in this trial

  • Erector Spinae Plane Block

    Procedure/Surgery

    dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries.

Treatment groups

90 Participants
are divided into 2 treatment groups
Group A: dexmedetomidine combined with bupivacaineActive comparator 1 intervention
Group B: dexamethasone combined with bupivacaineExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

VAS score

pain intensity using VAS score

Time frame
at 30 minutes, 2, 4, 6, 8, 12, 16, 20, and 24 hours postoperative.

Secondary outcomes

1

the time for requirement of first morphine dose

the time for requirement of first morphine dose (hours)

Time frame
at 30 minutes, 2, 4, 6, 8, 12, 16, 20, and 24 hours postoperative.

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Loay Gamal

Lead sponsor

Assiut University

Sponsor institution

This trial is not recruiting at the moment. You can still explore other options: