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Evaluation of 2%Bromelain Gel With 0.2%CHX Gel as Subgingival LDD Following SRP in Stage II/III and Grade B Periodontitis -A RCT

ConditionPeriodontal Pocket
Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age30-50
SponsorKrishnadevaraya College of Dental Sciences & Hospital

About this trial

The current study is a prospective randomised study Evaluation of 2%Bromelain Gel With 0.2%Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing in Stage II/III and Grade B Periodontitis

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Patient with have chronic periodontitis in the age group between 30-50 years.

Patients having ≥20 teeth.

Patients who are systematically healthy.

Patients with localized pockets with probing depth of ≤ 5mm.

Disqualifiers

Patients who have received any surgical or nonsurgical therapy during past 6months

Pregnant or lactating females.

Use of systemic antibiotics in the past 6 months.

Patient who are not willing to give a written informed consent

Trial design

Design model

Parallel

Treatments tested in this trial

  • Bromelain gel

    Drug

    bromelain gel is prepared from bromelain capsules in laboratory

  • chlorhexidine gel

    Drug

    chlorhexidine gel is prepared from mouth wash

  • SRP

    Procedure/Surgery

    Scaling and root planing was done with ultra sonic and hand scaling

Treatment groups

36 Participants
are divided into 3 treatment groups
Group A: GROUP 1-SRP aloneActive comparator 1 intervention
Group B: GROUP 2-0.2% BROMELAIN gelExperimental treatment 1 intervention
Group C: GROUP 3-0.2% CHLORHEXIDINE gelActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Probing pocket Depth (PPD)

measured using a UNC-15 probe (university of North Carolina-15 periodontal probe- Hu-Friedy, Chicago, IL, USA

Time frame
3 months
2

Relative attachment level (RAL)

(university of North Carolina-15 periodontal probe- Hu-Friedy, Chicago, IL, USA)

Time frame
3 months

Secondary outcomes

1

Plaque Index

measured on the tooth surface using a probe

Time frame
3 months
2

Gingival index

measured on the tooth surface using a probe

Time frame
3 month
3

Modified Sulcus Bleeding Index

measured on the tooth surface using a probe

Time frame
3 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Krishnadevaraya College of Dental Sciences & Hospital

Lead sponsor

Source ClinicalTrials.gov
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