Riptylimab for the Treatment of Optic Neuritis and Myelitis Spectrum Diseases

Trial statusNot yet recruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorZhongming Qiu

About this trial

This clinical trial aims to evaluate the safety and efficacy of ripertamab in patients with neuromyelitis optica spectrum disorders (NMOSD). The key research objectives are as follows:

1. To assess the efficacy of ripertamab for the treatment of neuromyelitis optica spectrum disorders. 2. To assess the safety of ripertamab for the treatment of neuromyelitis optica spectrum disorders.

Study participants are required to:

Receive a single intravenous infusion of ripertamab. Attend follow-up examinations and laboratory tests at the study site at Week 1, Week 9, Week 17, Week 25, Week 33, Week 41, Week 49, Week 57, Week 65, Week 73, Week 81, Week 89, Week 97.

Maintain a daily symptom diary and record the number of rescue treatments.

Eligibility criteria

Qualifiers

None

Disqualifiers

1. Any condition that, in the investigator's opinion, may interfere with the evaluation or administration of the study drug, assessment of patient safety, or interpretation of study results.

Trial design

Treatments tested in this trial

  • Riptylimab

Treatment groups

20 Participants
are divided into 1 treatment group

Locations

This trial has no locations

Sponsors and collaborators

Zhongming Qiu

Lead sponsor

Xinqiao Hospital of Chongqing

Sponsor institution