The goal of this clinical trial is to learn if a GalKO Porcine Thymokidney can maintain renal function, without the need for dialysis, after transplantation into adult subjects with End Stage Renal Disease.
ESRD receiving hemodialysis or peritoneal dialysis for ≥6 months
Eligible for kidney transplantation per site criteria
<50% likelihood of receiving a standard deceased-donor kidney transplant within 12 months
Blood type and immunologic compatibility with study transplant confirmed by testing
Requirement for multi-organ transplantation
Living donor available who is ABO-incompatible
Kidney disease with high risk of post-transplant recurrence
Polycystic kidney disease without prior native nephrectomy