Study of XmAb412 in Healthy Participants

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18-55
SponsorXencor, Inc.

About this trial

This Phase 1 Study will evaluate the safety, tolerability, pharmacokinectics and pharmacodynamics of XmAb412 in healthy adult participants

Eligibility criteria

Qualifiers

Age 18-55 years old

Must be in good health with no significant medical history

BMI 18-35 kg/m2

Contraceptive use consistent with local regulations

Disqualifiers

Any physical condition that prohibits study completion

Known hypersensitivity to the trial intervention or any of its components

HIV, hepatitis B and hepatitis C positive

Clinically significant abnormal ECG

Trial design

Treatments tested in this trial

  • XmAb412 Monoclonal Bispecific Antibody
  • Placebo

Treatment groups

128 Participants
are divided into 4 treatment groups

Sponsors and collaborators