Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age15-25
SponsorWashington University School of Medicine

About this trial

Use of vaping products (e.g., electronic nicotine delivery systems, e-cigarettes) has been increasing rapidly, particularly among teens and young adults. With limited information on the long-term effects of vaping products, health information about vaping has been somewhat unclear in regards to associated health risks. Teens and young adults may be reluctant to disclose their use of vaping products to parents or health providers and instead turn to social media to share and seek out information regarding vaping risks and cessation supports. Thus, our current proposal outlines the use of social media to identify teens and young adults socially networking about vaping, the use of an online chatbot screen to evaluate individual cessation support needs, and the use of a digital intervention system to support vaping cessation. The mobile intervention used in this study is based on a widely-used evidence-based mobile intervention for combustible smoking (i.e., quitSTART) and has been adapted for vaping and young adults to include an in-app chatbot to guide users to tailored content and to motivate and encourage their cessation efforts. We aim to integrate our social media recruitment and online screening approach to connect individuals with this mobile app intervention, and will conduct a randomized controlled trial to evaluate user engagement with and preliminary efficacy of the digital intervention on reducing vaping behaviors among teens and young adults.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

US Resident

English Speaking

Have daily access to a smartphone

Current vaping product user (P30D)

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • quitSTART Mobile Application

    Device

    Mobile application with educational content, motivational messages, self-monitoring, and tips for managing cravings to support vaping cessation among young adults.

  • Chatbot Feature in quitSTART Mobile Application

    Behavioral

    In-App chatbot feature emedded into quitSTART mobile application to motivate vaping cessation and support app navigation.

Treatment groups

189 Participants
are divided into 3 treatment groups
Group A: Control GroupNo intervention 0 interventions
Group B: Experimental Group A: Mobile App InterventionExperimental treatment 1 intervention
Group C: Experimental Group B: Mobile App Intervention with Embedded Chatbot FeatureExperimental treatment 2 interventions

Trial outcomes

Primary outcomes

1

Vaping cessation

Vaping cessation as assessed by 7 day self-reported vaping abstinence at follow-up. Timeline follow back procedures will be used to establish abstinence or if participants lapsed (their first instance of vaping post quit) or relapsed (vaped on 7 consecutive days) at each follow up time point.

Time frame
Baseline, 6 weeks, 3 months

Secondary outcomes

1

Nicotine dependence

Nicotine dependence will be assessed using the 4-item Patient-Reported Outcomes Measurement Information System (PROMIS).

Time frame
Baseline, 6 weeks, 3 months
2

Risk perception related to vaping

Perceived risks of vaping, both general and conditional, will be assessed with two items adapted from Wackowski et al., 2020. "How harmful, if at all, do you think vaping/using an e-cigarette is to a user's health?" (general) and "Imagine you vaped/used e-cigarettes daily for the next 10 years and used no other tobacco product. How harmful do you think this vaping would be to your health?" (conditional), both using a five-point response scale (not at all-extremely harmful).

Time frame
Baseline, 6 weeks, 3 months
3

Intervention engagement

Data automatically captured within the chatbot, and app platform will be used to calculate a composite measure of engagement for those randomized to each of these intervention components and will be examined as a predictor of outcomes. We will use a modified version of an app Engagement Index (EI).

Time frame
Baseline, 6 weeks, 3 months

Other outcomes

Sponsors and contacts

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Washington University School of Medicine

Lead sponsor

The University of Texas Health Science Center, Houston

Collaborator

University of South Carolina

Collaborator

National Institute on Drug Abuse (NIDA)

Collaborator