About this trial
Surgery is one of the most frequent treatments of colorectal cancer. However, delayed restoration of intestinal motility is a common phenomenon in patients who undergo colorectal surgery, and may reduce comfort, prevent the early hospital discharge of patients and increase healthcare costs. Gum chewing is a kind of safe and easily accessible sham feeding to stimulate intestinal motility. In addition, prediction models were used to estimate the risk of delayed restoration of intestinal motility after colorectal surgery. Thus, this study is an External Controlled trial that will determine whether stratified application of gum chewing by risk prediction model will enhance restoration of intestinal motility and reduce healthcare costs in paitents undergoing open or laparoscopic colorectal surgery.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients with newly diagnosed colorectal cancer
Undergo open or laparoscopic colorectal surgery
Able to give informed consent
With normal verbal skills
Disqualifiers
Preoperative lower extremity dysfunction
Dysphagia before surgery
Patients who are discharged ,transferred to another hospital or die within 72
hours after surgery
Trial design
Parallel
Treatments tested in this trial
gum chewing
Dietary supplementParticipants allocated to chewing gum will be instructed to chew commercially available sugar-free gum (Extra \& Reg, Wm. Wrigley Jr. Co., Ltd., Shanghai, China) three times daily from the first postoperative morning until oral dietary intake. They were instructed to chew the piece of gum for at least 10 minutes.
Treatment groups
Trial outcomes
Primary outcomes
first flatus time
time to the passage of first flatus
first defecation time
time to the first defecation
proportion of delayed restoration of intestinal motility
The proportion of delayed restoration of intestinal motility will be caculated as the number of participants with delayed restoration of intestinal motility divided by the total number of participants enrolled in the study
length of hospital stay
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options: