A Phase 2 Study of Sirolimus for Injection (Albumin-bound) in Patients With Progressive or Symptomatic Epithelioid Hemangioendothelioma

Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorCSPC ZhongQi Pharmaceutical Technology Co., Ltd.

About this trial

A Single-Arm, Non-Randomized, Open-Label Phase 2 Study of Nab-Sirolimus in Patients with Progressive or Symptomatic Epithelioid Hemangioendothelioma.

Detailed Description: Avoid duplicating information that will be entered or uploaded elsewhere in the record.

Eligibility criteria

Qualifiers

Renal function: Serum creatinine ≤ 1.5 × upper limit of normal (ULN).

Disqualifiers

Nitrosoureas (e.g., carmustine, lomustine) or mitomycin C: within 6 weeks prior to the first dose of study drug;

Oral fluoropyrimidines and small-molecule targeted agents: within 2 weeks prior to the first dose of study drug or within 5 known half-lives of the drug, whichever is longer;

Traditional Chinese medicines with anti-tumor indications: within 2 weeks prior to the first dose of study drug.

Received any other unapproved investigational product within 4 weeks prior to the first dose of study drug.

Trial design

Treatments tested in this trial

  • Sirolimus for injection (Albumin-bound)

Treatment groups

40 Participants
are divided into 1 treatment group