A Study Of Synthetic THC And Sleep
ConditionObstructive Sleep Apnea
Trial statusNot yet recruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age21-70
SponsorMayo Clinic
About this trial
The purpose of this study is to determine if oral dronabinol prior to sleep can improve CPAP adherence and sleep quality in humans. We also seek to determine if combination therapy of CPAP and pre-sleep dronabinol is associated with improved BP regulation. We will also explore BP regulatory mechanisms and whether these are impacted differently between traditional CPAP therapy and combination CPAP/dronabinol.
Eligibility criteria
Qualifiers
21 - 70 years of age
Biological male or female
AHI between 15 - 50 events/hour
Current or new OSA diagnosis
Disqualifiers
BMI > 35 kg/m2
Diagnosed psychiatric disorders
Hypotension
History of seizures
Trial design
Treatments tested in this trial
- Dronabinol
- Placebo
Treatment groups
72 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov