A Study on the Effects of Exercise Therapy on Signs of Prostate Cancer

ConditionsProstate Cancer Prostate Adenocarcinoma Localized Prostate Carcinoma

Trial statusRecruiting

Trial phasePhase 2

Trial typeInterventional

Biological sexMale

Age18+

SponsorCity of Hope Medical Center

About this trial

To determine the effects of exercise therapy on molecular, radiologic, and pathologic nimbosus hallmarks versus usual care control in men on Active Surveillance for localized prostate cancer.

Eligibility criteria

Qualifiers

Age ≥ 18

Men with histologically confirmed localized prostate cancer undergoing active surveillance.

Inactive, defined as not meeting the national exercise guidelines for cancer patients (<150 minutes/week of moderate or vigorous exercise)43 as assessed by remote activity and heart rate tracking for a 7-day period prior to study entry (general physical activity screening assessment via smart watch).

Screening clearance by an MSK Exercise Physiologist (i.e., review of ECG)

Disqualifiers

Enrollment in any other program that may alter the impact of exercise on tumor outcomes (e.g., weight loss program)

Any neoadjuvant anticancer treatment of any kind for prostate cancer in the last 5 years

Any history of systemic anticancer therapy in the last 15 years

Distant metastatic malignancy of any kind

Trial design

Treatments tested in this trial

Exercise Therapy

Treatment groups

102 Participants

are divided into 2 treatment groups

Locations10

Select a site below to view it on the map.

Sponsors and collaborators

City of Hope Medical Center

Lead sponsor

Source ClinicalTrials.gov