Adrenaline Nasal Pack vs Xylometazoline Nasal Drops During Nasotracheal Intubation
Trial statusRecruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age18-60
SponsorShaheed Mohtarma Benazir Bhutto Institue of Trauma
About this trial
The goal of this trial is to compare efficacy of xylometazoline nasal drops and adrenaline nasal pack in participants undergoing elective oromaxillofacial surgeries.
The main question aim to answer is xylometazoline nasal drops better than adrenaline nasal packing in terms of nasal bleeding during nasotracheal intubation. Researchers are comparing 2 groups of participants.
Participants in group Xylometazoline are receiving 0.1% xylometaxoline nasal drops.
Participants in group Adrenaline are receiving adrenaline nasal packing.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
ASA 1 and 2
Age group between 18-60 years
Mallampati score 1 and 2
Either gender
Disqualifiers
Lack of consent
Participants with anticipated difficult airway
Participants receiving anticoagulant therapy
History of nasal abnormality (nasal surgery, trauma, polyp, obstruction)
Trial design
Design model
Parallel
Treatments tested in this trial
0.1% xylometazoline nasal drops
DrugXylometazoline is direct acting, non selective, adrenergic agonist binding with alpha 1\&2 receptors, used for vasoconstriction to decrease nasal bleeding.
Adrenaline nasal pack
DrugAdrenaline is direct acting, non selective, adrenergic agonist binding with alpha and beta receptors both, used for vasoconstriction to decrease nasal bleeding.
Treatment groups
70 Participants
are divided into 2 treatment groupsGroup A: Xylometazoline GroupExperimental treatment 1 intervention
Group B: Adrenaline GroupActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Nasal bleeding
Time frame
At the time of Intubation and ExtubationSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov