Comparing of Sesame Oil, Nitroglycerin Ointment, and Aloe Vera Gel

ConditionsCancer Chemotherapy

Trial statusNot yet recruiting

Trial phasePhase 2

Trial typeInterventional

Biological sexAll

AgeNot listed

SponsorUniversity of Basrah

About this trial

compare the effectiveness sesame oil, aloe Vera gel, and nitroglycerin ointment prevention of phlebitis.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

adult conscious patients of both gender.

Patients receiving chemotherapy antimetabolites (5-fluorouracil).

Patients receiving chemotherapy alkylating agents (Cisplatin).

Patients receiving chemotherapy through peripheral IV cannula.

Disqualifiers

Phlebitis has already appeared at the IV infusion site.

Patients using port or central venous catheters to administer chemotherapy. - Patient radiation therapy, immunity therapy and palliative therapy

Patients receiving chemotherapy (antitumor antibiotics, plant alkaloids).

Trial design

Design model

Parallel

Treatments tested in this trial

Sesame Oil
Biological/Vaccine
10 drops (3 mL) of 100% pure sesame oil in a circular motion for 5 minutes within 10 cm on the anterior forearm of the chemotherapy patient. T
Aloe vera gel
Biological/Vaccine
soak the skin in 5 cc of Aloe vera gel, drawn with a syringe, in a circular motion for 20 minutes within 10 cm on the anterior forearm of the chemotherapy patient.
Control
Other intervention
without any intervention
nitroglycerin ointment
Biological/Vaccine
The researchers will apply nitroglycerin ointment in a circular motion for 5 minutes over a 10 cm area on the anterior forearm of the chemotherapy patient.

Treatment groups

190 Participants

are divided into 4 treatment groups

Group A: sesame oilExperimental treatment 1 intervention

Group B: Aloe Vera gelExperimental treatment 1 intervention

Group C: nitroglycerin ointmentExperimental treatment 1 intervention

Group D: controlOther 1 intervention

Trial outcomes

Primary outcomes

Phlebitis Scale

Multiple measurements will be aggregated to arrive at one reported value (phlebitis) that consists of five symptom grades were included in the chemotherapy-induced phlebitis severity scale, ranging from zero to four in severity. The National Cancer Institute Common Terminology Criteria for Adverse Events version 4 (NCI-CTCAE) (41). Which is widely used by clinical oncologists, served as the basis for the selection of grading levels. Grade zero denotes no symptoms); (grade one mild), ( grade two moderate), ( grade three marked) (and grade four severe).

Time frame

24-48 hours

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Basrah

Lead sponsor

University of Baghdad

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: