Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-89
SponsorTeachers College, Columbia University

About this trial

The goal of this clinical trial is to compare the effectiveness of traditional Semantic Feature Analysis (SFA) treatment to a modified SFA protocol that includes Metacognitive Strategy Training (SFA+MST) for adults with acquired aphasia. The main questions it aims to answer are:

* What are the comparative outcomes in picture naming accuracy and strategy use during picture naming following 2 months of traditional SFA versus SFA + MST in adults with acquired aphasia? * What are the comparative outcomes in percent of informative content and rate of informative content during spontaneous speech production following 2 months of traditional SFA versus SFA + MST in adults with acquired aphasia?

Researchers will compare outcomes between these two treatments to see if SFA+MST yields larger effects in picture naming and spontaneous speech outcomes than traditional SFA.

Participants will complete:

* 5-7 pre-treatment assessment sessions where they will be asked to name pictures, tell stories/describe pictures, answer questions, and complete questionnaires, * 3 treatment sessions of SFA \*OR\* SFA+MST per week for 8 weeks, for a total of 24 sessions, * 7 weekly probes (i.e., short, intermittent assessments throughout the treatment phase), * 3 post-treatment assessment sessions immediately after treatment ends, where they will complete the same assessment tasks as they did pre-treatment (e.g., naming pictures, telling stories, etc.), * 2 retention assessment sessions, one 30 days and the other 60 days following the final treatment session, where they will be asked to name pictures, tell stories/describe pictures, and describe what they learned during the study.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Have aphasia due to a single acute event (e.g., left-hemisphere stroke, traumatic brain injury)

Be at least six-months post aphasia-onset,

Be a proficient English speaker,

Have normal or corrected to normal hearing (i.e., hearing aids) and vision (i.e., eyeglasses),

Disqualifiers

A history of neurodegenerative disease (e.g., dementia), severe motor speech disorder, significant mental illness, psychiatric disorder, drug/alcohol abuse, or neurological condition that could influence their cognitive, language, and memory systems,

Children under the age of 18,

Adults over the age of 89,

Uncorrected hearing and vision.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Semantic Feature Analysis (traditional)

    Behavioral

    This treatment involves naming pictures of objects, describing the objects' features (e.g., category membership, physical attributes, etc.), and creating sentences using the objects' names. It does not include direct metacognitive strategy training.

  • Semantic Feature Analysis + Metacognitive Strategy Training

    Behavioral

    This treatment involves metacognitive teaching and practice, naming pictures of objects, describing the objects' features (e.g., category membership, physical attributes, etc), creating sentences using the objects' names, debriefing on overall performance, and discussing recent and future opportunities for strategy implementation in real life.

Treatment groups

40 Participants
are divided into 2 treatment groups
Group A: Traditional Semantic Feature AnalysisActive comparator 1 intervention
Group B: Semantic Feature Analysis + Metacognitive Strategy TrainingExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Confrontation naming accuracy

Participants will complete a 60-item confrontation naming assessment before, during, and after treatment. We will calculate the total number of items that participants name accurately across study phases.

Time frame
Change from Baseline through study completion, an average of 6 months
2

Independent word-finding strategy use

Using the 60-item confrontation naming assessment, we will evaluate instances in which participants independently use a specific word-finding strategy (describing or talking around the word) in instances where they cannot name items successfully, and calculate the proportions of incorrect responses with and without strategy use across study phases.

Time frame
Change from Baseline through study completion, an average of 6 months

Secondary outcomes

1

Discourse informativeness

Participants will describe picture scenes and tell stories. We will calculate the amount of informative content in their descriptions/stories using Content Information Unit (%CIU; Nicholas \& Brookshire, 1993) analysis for descriptions/stories across study phases.

Time frame
Change from Baseline through study completion, an average of 6 months
2

Discourse efficiency

Participants will describe picture scenes and tell stories. We will calculate the rate of informative content in their descriptions/stories using Content Information Unit (CIU/minute; Nicholas \& Brookshire, 1993) analysis for descriptions/stories across study phases.

Time frame
Change from Baseline through study completion, an average of 6 months

Other outcomes

1

Explicit strategy knowledge

Participants will be asked to identify what they can do in moments of word-finding difficulty and what types of information they can provide in those moments, across study phases. There are six types of information that will be discussed during the treatments.

Time frame
Change from Baseline through study completion, an average of 6 months

Sponsors and contacts

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