Effect of Pre-medication With Anti-inflammatory Drugs(Ibuprofen and Dexamethasone)on Post-Endodontic Pain

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-50
SponsorArmed Forces Institute of Dentistry, Pakistan

About this trial

Effect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain with symptomatic irreversible pulpitis

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Permanent teeth with acutely inflamed pulp without swelling or draining sinus.

Patients of either gender aged between 18-50 years old.

Systemically healthy patients.

Patients who agree to attend for recall appointments and provide a written consent.

Disqualifiers

Patients on preoperative analgesics and antibiotics.

Teeth with calcified canals and previously treated teeth.

Pregnant and lactating mothers.

Patients who are immunocompromised, anxious and mentally handicapped.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Anti-inflammatory drug (ibuprofen)

    Drug

    Effect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain

  • Anti-inflammatory drug (dexamethsaone)

    Drug

    Effect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain

Treatment groups

130 Participants
are divided into 2 treatment groups
Group A: Pain with ibuprofenActive comparator 1 intervention
Group B: Pain with dexamethasoneActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

effect of pre-medication(ibuprofen and dexamethasone ) on post-endodontic pain

Effect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain on visual analogue scale

Time frame
24 hours
2

effect of pre-medication(ibuprofen and dexamethasone ) on post-endodontic pain

Effect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain on visual analogue scale

Time frame
48 hours
3

effect of pre-medication(ibuprofen and dexamethasone ) on post-endodontic pain

Effect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain on visual analogue scale

Time frame
72 hours

Secondary outcomes

Other outcomes

Sponsors and contacts

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