About this trial
The purpose of this study is to compare the efficacy and safety of ICP-332 to placebo in participants with moderate-to-severe plaque psoriasis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Subjects voluntarily participate in this study and have signed the Informed Consent Form (ICF).
Male or female subjects aged ≥ 18 years and ≤ 70 years
A history of plaque psoriasis for ≥6 months at baseline
Psoriasis Area and Severity Index (PASI) score ≥12
Disqualifiers
Diagnosed with non-plaque psoriasis.
Subject had laboratory values meeting any of the protocol-specified criteria at Screening.
Presence of clinically serious, progressive, or uncontrolled disease.
Previous history of alcoholism or drug abuse (except for those who have been completely abstinent for more than 6 months before randomization).
Trial design
Parallel
Treatments tested in this trial
ICP-332 Tablets
DrugICP-332 will be administered as tablet for 12 weeks
ICP-332 Tablets
DrugICP-332 will be administered as tablet for 12 weeks
ICP-332 Tablets
DrugICP-332 will be administered as tablet for 12 weeks
ICP-332 Placebo Tablets
Other interventionPlacebo will be administered as tablet for 12 weeks
Treatment groups
Trial outcomes
Primary outcomes
The Percentage of Participants With Moderate to Severe Psoriasis Experiencing a 75% Improvement (Reduction From Baseline) in PASI Score (PASI-75 Response Rate) at Week 12
Sponsors and contacts
Click on the lead sponsor to view all of their trials.