Health TrialsbyHealthPanel

Micro-Needling Technique Using Ozonated Olive Oil in Periodontal Diseases

ConditionsPeriodontal DiseasesPeriodontitis and Treatment NeedGingivitis
Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-60
SponsorFayoum University

About this trial

The research idea is based on using micro-acupuncture therapy with ozone-treated olive oil to improve the condition of patients suffering from gingivitis and periodontitis and comparing it to the scientifically proven conventional treatment. This is a randomized controlled study, and this idea was chosen from the current general trend in medicine, particularly in dentistry, to use natural sources for treatment due to fewer side effects compared to the chemicals used.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 18-60 years old

Male and female medically free participants

Patients suffering from biofilm induced gingivitis or periodontitis

Disqualifiers

Smoking and tobacco related habits

Non-biofilm induced gingival diseases

Necrotizing periodontal diseases

periodontitis as a manifestation of systemic disease

Trial design

Design model

Parallel

Treatments tested in this trial

  • microneedling

    Other intervention

    gingival microneedling (small holes in gingiva)

  • scaling

    Other intervention

    scaling (plaque removal)

  • Ozonated olive oil

    Biological/Vaccine

    ozonated olive oil after microneedling

Treatment groups

30 Participants
are divided into 3 treatment groups
Group A: biofilm induced gingivitis treated with microneedling & topical ozonated olive oil.Experimental treatment 3 interventions
Group B: Periodontitis cases treated by scaling only.Experimental treatment 1 intervention
Group C: Periodontitis cases treated with microneedling and topical ozonated olive oil.Experimental treatment 3 interventions

Trial outcomes

Primary outcomes

1

bleeding on probing

Muehlemann \& Son index

Time frame
4 weeks
2

Plaque index

Silness-Loe Plaque Index

Time frame
4 weeks
3

probing depth and clinical attachment loss

measured in mm using a UNC 15 probe

Time frame
4 weeks

Secondary outcomes

1

malondialdehyde and 8-hydroxy-deoxyguanosin level in GCF.

measured by ELISA

Time frame
4 weeks

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Fayoum University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: