About this trial
Smell dysfunction significantly impacts quality of life and safety, with limited effective treatments. This open-label study evaluates the preliminary efficacy of combining non-invasive trigeminal nerve stimulation (TNS) with standard smell training (ST) to improve olfactory function. Participants will complete 8 weeks of at-home treatment and attend three in-person visits for assessment. Improvements in smell, mood, sleep, and quality of life will be measured.
Eligibility criteria
Qualifiers
Age 18-80
Self-reported or medically documented smell loss
Treatment-seeking for their smell loss
Naïve to TNS
Disqualifiers
Medical Records not available to confirm eligibility
Documented/Suspected head injury (e.g. sport, accident, blast exposure)
Neurological disorder (e.g. epilepsy, neurodegenerative disorder)
Serious mental illness (e.g. schizophrenia, bipolar disorder)
Trial design
Treatments tested in this trial
- Trigeminal Nerve Stimulation-enhanced Smell Training