About this trial
Overdose is a national top-three leading cause of pregnancy-associated death, and maternal substance use disorder (SUD) accounts for an estimated $1.5 billion in healthcare spending each year. Treatment with medication and behavioral therapy lowers morbidity and overdose risk. However, studies have shown 55% to 80% of patients stop treatment within one year postpartum. Additionally, as a result of systemic inequities, historically marginalized patients are at greatest risk of overdose or death. We are conducting a study at WashU Medicine and University of Maryland, Baltimore clinics that offer prenatal care, addiction treatment, and extended postpartum support for patients facing the challenges of a SUD. Study participants will complete a structured screening and management of their social needs, and then will be randomly assigned to continue their usual care or to participate in a contingency management program, which provides incentives to continue treatment.
Eligibility criteria
Qualifiers
Confirmed viable intrauterine pregnancy at any gestational age; OR postpartum with at least six months remaining until 365 days after deliver
Diagnosis of SUD as defined by DSM-5 and/or as documented in the clinical record
18 years of age or older
Two or more positive domains in first screening for social drivers of health
Disqualifiers
Declining follow-up care at participating study site
Participated in R61 pilot study for CM
Requiring immediate hospitalization for unstable medical or psychiatric conditions making patient clinically unsuitable for research participation at the time of enrollment approach
Unable to participate in English
Trial design
Treatments tested in this trial
- Contingency Management
- Social Drivers of Health Screening
Treatment groups
Sponsors and collaborators
Washington University School of Medicine
Lead sponsor
University of Maryland, Baltimore
Collaborator