Various Procedural Treatment Options for Post-acne Atrophic Scars
ConditionPost-acne Atrophic Scars
Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age13-50
SponsorSheikh Zayed Medical College
About this trial
Post acne scars are formed as a result of very inflamed and nodulocystic acne. Most common type of acne scars are atrophic scars and they are further classified on the basis of depth and size of destruction into ice pick, boxcar and rolling scars. Evaulating the most efficacious, safe and affordable treatment option is the need of the hour. This study is going to compare the efficacy of microneedling with autologous platelet rich plasma verses microneedling with topical insulin in the treatment of post-acne atrophic scars as to find out the relatively more effective and safer treatment.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age: 13-50 years
Gender: both male and female
Type of acne scar: Atrophic acne scar
Patients not taking prior treatment in last 1-2 months
Disqualifiers
Pregnancy and lactating females
Bleeding disorders
Platelet count less than 100000
Hypersensitivity to insulin, PRP
Trial design
Design model
Parallel
Treatments tested in this trial
micro-needling with topical human actrapid insulin
Procedure/SurgeryMicro-needling with topical application of 2ml of human actrapid insulin once monthly for 4 months
Micro-needling with topical Platelet rich plasma
Procedure/SurgeryMicro-needling with topical application of 2ml Platelet rich plasma once monthly for 4 months
Treatment groups
60 Participants
are divided into 2 treatment groupsGroup A: Micro-needling with topical human actrapid insulin group (Group A)Active comparator 1 intervention
Group B: Micro-needling with topical Platelet rich plasma(Group B)Active comparator 1 intervention
Trial outcomes
Primary outcomes
1
To compare the outcome of microneedling with autologous platelet rich plasma verses microneedling with topical insulin in the treatment of post-acne atrophic scars
Efficacy will be assesssed clinically at each follow up visit. Final efficacy of each treatment will be determined at last follow up visit( i.e. at 6th month after start of treatment).The final efficacy will be divided into following groups on the basis of clinical resolution of disease: 1.Remission: It is defined as complete resolution of all scar leaving behind normal skin. 2.Improvement: It is defined as a more than 50% healing of scars ,as clinically measured by the surface area from the baseline. 3.No improvement: It is defined as less than a 50% improvement in the healing of scars, as measured clinically by the surface area from the baseline.
Time frame
Clinical assessment for efficacy will be done monthly for 6 monthsSponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: