Health TrialsbyHealthPanel

Vitamin C Effectiveness in Preventing Urinary Tract Infections After Gynecological Surgeries

ConditionCatheter-Associated Urinary Tract Infection
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexFemale
Age18-80
SponsorAmerican University of Beirut Medical Center

About this trial

Double-blind placebo-controlled randomized trial aiming to assess the role of Vitamin C supplementation in the prevention of catheter-associated urinary tract infections in women undergoing elective gynecological surgeries.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Nonpregnant women

18 years of age or older

Undergoing elective GYN surgery

Disqualifiers

Pregnant women

Already taking Vitamin C supplementation

Nephrolithiasis

Congenital anomaly or neurogenic bladder

Trial design

Design model

Parallel

Treatments tested in this trial

  • Ascorbic Acid 1000 MG

    Drug

    1000mg Ascorbic acid orally daily started on the day of elective gynecological surgery for 10 days

  • Placebo

    Drug

    Placebo tablet daily starting day of elective gynecological surgery for 10 days

Treatment groups

180 Participants
are divided into 2 treatment groups
Group A: Vitamin CActive comparator 1 intervention
Group B: PlaceboPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

Incidence of UTI

The Primary endpoint is the proportion of participants who experience a clinically diagnosed and treated UTI as evidenced by a positive urine culture.

Time frame
30 days

Secondary outcomes

1

Asymptomatic UTI

The proportion of participants with a positive urine culture, while asymptomatic (asymptomatic bacteriuria) at the end of the study period

Time frame
30 days

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

American University of Beirut Medical Center

Lead sponsor

Moscow State University of Medicine and Dentistry

Collaborator

Source ClinicalTrials.gov
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