Warm Versus Conventional 2% Lignocaine for IANB Efficacy
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-50
SponsorArmed Forces Institute of Dentistry, Pakistan
About this trial
The study compares the anesthetic efficacy of warm versus conventional 2% lignocaine for inferior alveolar nerve block in mandibular molars, evaluating success rates and onset time.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Permanent teeth with acutely inflamed pulp without swelling or draining sinus.
Patient who have carious mandibular molars.
Patients of either gender aged between 18-50 years old.
Systemically healthy patients.
Disqualifiers
Patients on preoperative analgesics and antibiotics.
Teeth with calcified canals and previously treated teeth.
Pregnant and lactating mothers.
Patients who are immunocompromised, anxious and mentally handicapped.
Trial design
Design model
Parallel
Treatments tested in this trial
conventional 2% lignocaine at room temperature
DrugThis study aims to compare the effectiveness of warm 2% lignocaine (lidocaine) versus conventional room temperature 2% lignocaine for achieving successful inferior alveolar nerve blocks (IANB) in mandibular permanent molars
pre-warmed 2% lignocaine at 42°C
DrugThis study aims to compare the effectiveness of warm 2% lignocaine (lidocaine) versus conventional room temperature 2% lignocaine for achieving successful inferior alveolar nerve blocks (IANB) in mandibular permanent molars
Treatment groups
200 Participants
are divided into 2 treatment groupsGroup A: conventionalActive comparator 1 intervention
Group B: warm (42 celsius)Active comparator 1 intervention
Trial outcomes
Primary outcomes
1
Pain during administration of injection
Pain during administration of injection with 2% conventional and warm lignocaine on visual analogue scale is assessed. Visual Analog Scale, which is a tool used to measure a patient's perception of pain. It typically consists of a line, often 10 cm long, where one end represents "no pain" and the other end represents "worst possible pain." The patient marks a point on the line that corresponds to their level of pain. The distance from the "no pain" end to the point marked by the patient is then measured, usually in centimeters or millimeters, to quantify the pain intensity. Visual Analog Scale is commonly used in clinical trials to assess pain during and after procedures, as it provides a simple and reliable method for evaluating pain intensity.
Time frame
60 seconds2
Onset of anesthesia in seconds
It will be measured by gingival probing every 15 seconds till patient reports no sensation after stimulus (assessed up to 15 minutes after anesthesia application) It will be done by using both conventional and warm 2% lignocaine.
Time frame
Every 15 seconds till patient reports no sensation after stimulus (assessed up to 15 minutes after anesthesia application)Sponsors and contacts
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Source ClinicalTrials.gov