Xengenic Cortical Membranes Versus Connective Tissue Graft With Coronally Advanced Flap for the Treatment of Peri-implant Soft Tissue Dehiscences: A Randomized, Controlled Clinical Trial

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age20-50
SponsorAmr Anwar Mohamed Ellithy Yousef

About this trial

Peri-implant soft tissue dehiscences represent a common complication in implant dentistry, often leading to esthetic and functional challenges. Current treatment options, including Xengenic cortical membranes and connective tissue graft with coronally advanced flap, aim to promote soft tissue regeneration and improve clinical outcomes. However, there is a need for comparative studies to determine the optimal treatment modality for peri-implant soft tissue dehiscences.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults (20-50) years old. •peri-implant soft tissue dehiscence . •Thin gingival phenotype. •Optimal compliance as evidenced by no missing treatment appointments and positive attitude towards oral hygiene.

Disqualifiers

•Medically compromised patients and systemic conditions precluding implant and periodontal surgery. •Smokers, diabetics, pregnant or lactating women. •History of chemotherapy, radiotherapy in head and/or neck region. •Bisphosphonate therapy.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Xengenic Cortical membranes

    Device

    soft tissue surgery around dental implant dehiscence

  • connective tissue graft

    Procedure/Surgery

    soft tissue surgery around dental implant dehiscence

Treatment groups

20 Participants
are divided into 2 treatment groups
Group A: Xengenic Cortical membranesExperimental treatment 1 intervention
Group B: connective tissue graftActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

peri implant soft tissue thickness

Time frame
six months

Secondary outcomes

1

pink esthetic score

Time frame
six months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Amr Anwar Mohamed Ellithy Yousef

Lead sponsor

Tanta University

Sponsor institution