The purpose of this study is to assess headache response rate for minimal pain at 30 minutes following zavegepant administration and to assess additional effectiveness and treatment failure endpoints at various timepoints after zavegepant administration
A diagnosis of episodic cluster headache according to the International Classification of Headache Disorders 3rd edition
A history of at least 2 prior headache bouts
Onset of cluster headache before age 50 years
Cluster headache attacks last a minimum duration of 45 minutes (if untreated)
Pregnant or breastfeeding patients.
Inability to follow training instructions for use of nasal device.
Unable to speak or read English.
Unable to access the internet (for the Questionnaires / Case Report Forms).
The University of Texas Health Science Center, Houston
Lead sponsor
Pfizer
Collaborator