Acute Sodium Bicarbonate Supplementation in Female Basketball Players
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexFemale
Age16-35
SponsorKrzysztof Durkalec-Michalski
About this trial
This randomized, double-blind, placebo-controlled crossover study aims to evaluate the effect of acute sodium bicarbonate supplementation, compared with placebo, on physical capacity and blood biochemical marker concentrations in highly trained female basketball players.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
female sex,
age 16 to 35 years,
good general health condition and well-being,
regular menstrual cycles,
Disqualifiers
male sex,
use of hormonal contraceptives,
current injury or musculoskeletal condition limiting participation in training or competition,
health-related or medical contraindications, including menstrual disorders, planned pregnancy, or anemia,
Trial design
Design model
Crossover
Treatments tested in this trial
Sodium Bicarbonate (NaHCO3)
Dietary supplementSodium bicarbonate supplementation; Participants will receive a single oral dose of sodium bicarbonate (SB) at 0.3 g/kg body mass, administered in opaque gelatin capsules 90 minutes before the exercise protocol during the first intervention visit.
Placebo
Other interventionParticipants will receive a single oral dose of placebo (PL), administered in identical opaque gelatin capsules 90 minutes before the exercise protocol during the first intervention visit.
Treatment groups
100 Participants
are divided into 2 treatment groupsGroup A: Sodium bicarbonateExperimental treatment 1 intervention
Group B: PLA treatmentPlacebo comparator 1 intervention
Trial outcomes
Primary outcomes
1
Changes in anaerobic power during the repeated modified Wingate Anaerobic Test
Assessment of peak power (PP), average power (AP), minimum power (MP), and power drop (PD) \[W (watts)\] during the repeated modified Wingate Anaerobic Test using the Monark 894E cycle ergometer (Monark, Sweden)
Time frame
At the Day 0 (familiarization visit), Day 7 (baseline visit), Day 14 (experimental visit 1), and Day 21 (experimental visit 2)2
Changes in interval mean power during the repeated modified Wingate Anaerobic Test
Assessment of mean power \[W (watts)\] in predefined 5 second intervals, including 1 to 5 s and 6 to 10 s, during each 10 second effort of the repeated modified Wingate Anaerobic Test using the Monark 894E cycle ergometer (Monark, Sweden)
Time frame
At the Day 0 (familiarization visit), Day 7 (baseline visit), Day 14 (experimental visit 1), and Day 21 (experimental visit 2)3
Changes in second-by-second power output during the repeated modified Wingate Anaerobic Test
Assessment of power output \[W (watts)\] for each 1 second segment, including 1 s, 2 s, 3 s, 4 s, 5 s, 6 s, 7 s, 8 s, 9 s, and 10 s, during each 10 second effort of the repeated modified Wingate Anaerobic Test using the Monark 894E cycle ergometer (Monark, Sweden)
Time frame
At the Day 0 (familiarization visit), Day 7 (baseline visit), Day 14 (experimental visit 1), and Day 21 (experimental visit 2)4
Changes in time to peak power during the repeated modified Wingate Anaerobic Test
Assessment of time to peak power (TTP) \[s (seconds)\] during each 10 second effort of the repeated modified Wingate Anaerobic Test using the Monark 894E cycle ergometer (Monark, Sweden)
Time frame
At the Day 0 (familiarization visit), Day 7 (baseline visit), Day 14 (experimental visit 1), and Day 21 (experimental visit 2)Secondary outcomes
1
Changes in oxygen uptake, carbon dioxide production, and minute ventilation during the repeated modified Wingate Anaerobic Test
Assessment of oxygen uptake (VO₂), carbon dioxide production (VCO₂), and minute ventilation (VE) \[L/min\] during the repeated modified Wingate Anaerobic Test using the K5 wearable metabolic system (Cosmed, Italy)
Time frame
At the Day 0 (familiarization visit), Day 7 (baseline visit), Day 14 (experimental visit 1), and Day 21 (experimental visit 2)2
Changes in relative oxygen uptake during the repeated modified Wingate Anaerobic Test
Assessment of relative oxygen uptake (VO₂), and carbon dioxide production (VCO₂) \[mL/kg/min\] during the repeated modified Wingate Anaerobic Test using the K5 wearable metabolic system (Cosmed, Italy)
Time frame
At the Day 0 (familiarization visit), Day 7 (baseline visit), Day 14 (experimental visit 1), and Day 21 (experimental visit 2)3
Changes in respiratory exchange ratio during the repeated modified Wingate Anaerobic Test
Assessment of respiratory exchange ratio (RER) \[ratio\] during the repeated modified Wingate Anaerobic Test using the K5 wearable metabolic system (Cosmed, Italy)
Time frame
At the Day 0 (familiarization visit), Day 7 (baseline visit), Day 14 (experimental visit 1), and Day 21 (experimental visit 2)4
Changes in breathing frequency during the repeated modified Wingate Anaerobic Test
Assessment of breathing frequency (BF) \[breaths/min\] during the repeated modified Wingate Anaerobic Test using the K5 wearable metabolic system (Cosmed, Italy)
Time frame
At the Day 0 (familiarization visit), Day 7 (baseline visit), Day 14 (experimental visit 1), and Day 21 (experimental visit 2)Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Krzysztof Durkalec-Michalski
Lead sponsor
Poznan University of Physical Education
Sponsor institution
Source ClinicalTrials.gov