Comparative Study Between Platelet Rich Plasma and Steroid Injection in Trigger Finger Treatment

Trial statusNot yet recruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorObafemi Awolowo University Teaching Hospital

About this trial

The goal of this clinical trial is to learn if platelet rich plasma works to treat early stage trigger finger in adults. It will also learn about the safety platelet rich plasma. The main questions it aims to answer are:

Does platelet rich plasma lower the pain associated with trigger finger of participants? Does it improve the hand grip strength and Q DASH score of participants? Researchers will compare platelet rich plasma to Depo-Medrol steroid (a known standard of care for early stage trigger finger) to see if platelet rich plasma works to treat early trigger finger.

Participants will:

Take platelet rich plasma or a depo-medrol steroid intralesional injection at recruitment into the intervention Visit the clinic once every 4 weeks for checkups and parameter measurements. Investigator will will keep a record of participants progress in symptom remission

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients who are 18year and above with mild or moderate trigger finger, who are willing to have intra-lesional administration of blood product.

Disqualifiers

Previous steroid injection

Previous Surgery to that finger

Thrombocytopenic patients

Hand and finger contracture

Trial design

Design model

Single group

Treatments tested in this trial

  • Platelet rich plasma

    Biological/Vaccine

    Freshly prepared autologus platelet rich plasma

  • Pfizer Depo-medrol

    Drug

    Methylprednisolone acetate 20mg/ml injection

Treatment groups

40 Participants
are divided into 2 treatment groups
Group A: Group AExperimental treatment 1 intervention
Group B: Group BActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

symptom resolution post injection

reduction of pain using VAS and absence snapping of finger

Time frame
3 months

Secondary outcomes

1

Hand grip strength

measured grip using hand dynamomter

Time frame
3 month
2

Q- DASH score

11-item self reported disability questionnaire that consider upper extremity as one functional unit

Time frame
3month

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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