Comparison of Bupivacaine Wound Infiltration Versus Wound Instillation to Minimize Postoperative Pain After Thyroid Surgery

Trial statusNot yet recruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssiut University

About this trial

Pain management following thyroidectomies, which can cause mild to moderate postoperative pain, particularly in the first 24 hours following surgery, has received little attention . The incision of the wound, neck hyperextension, retraction of the wound margins during surgery, and dissection are the main reasons of post-thyroidectomy discomfort . After thyroid surgery, pain management improves patients' quality of life and facilitates a speedy return to regular daily activities.

the aim of the study to evaluate the effects of bupivacaine instillation after thyroidectomy against infiltration into the surgical field in order to reduce postoperative discomfort following thyroid surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Normal thyroid function patients of both genders scheduled for thyroid surgery will included in this study

If they are over the age of 18

If they had an ASA score (American Society of Anesthesiology) I, II.

A Score of Mallampati I , II.

Disqualifiers

Patient refused to participate in the study.

Patients will be excluded if they have any analgesic medication or corticosteroid drug prior surgery or

A known or suspected allergy to local anesthetics,

if the duration of surgery is greater than 5 h and if a major complication of surgery or anesthesia (major bleeding, allergy to anesthetic products).

Trial design

Design model

Parallel

Treatments tested in this trial

  • Bupivacaine

    Drug

    the patients will receive the content of a syringe (10 ml of bupivacaine 0.25%)

  • Adrenaline

    Drug

    the patients will receive the content of a syringe 15 μg adrenaline

  • Lidocaine (drug)

    Drug

    the patients will receive the content of a syringe 70 ml Lidocaine .

Treatment groups

102 Participants
are divided into 2 treatment groups
Group A: Group SActive comparator 3 interventions
Group B: Group FActive comparator 3 interventions

Trial outcomes

Primary outcomes

1

Total analgesic consumption

Total analgesic consumption at 1st. 24 hours postoperative

Time frame
24 hours

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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