Effect of Pentoxyfilline on Endometrial Thickness and Frozen Embryo Transfer Outcomes
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexFemale
Age18-43
SponsorBeni-Suef University
About this trial
The aim of this work was to investigate the effect of different vasodilators as pentoxifylline in women with unexplained infertility using IVF
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
as good quality day five frozen embryos.
Disqualifiers
history of endocrine diseases,
history of any previous surgery that couldm compromise the integrity of endometrium,
cardiovascular, renal and liver diseases,
Trial design
Design model
Parallel
Treatments tested in this trial
pentoxifylline 400 mg
DrugOnce daily in form of (Trental ® Sanofi co.) daily in addition to the above treatment protocol from the first day of the cycle until the day of starting progesterone.
(control)
Other interventionestradiol valerate 2 mg. in form of (Cycloprogynova® Bayer Shering Pharma) whitepills starting dose is one pill T.I.D
Treatment groups
100 Participants
are divided into 2 treatment groupsGroup A: (control)Active comparator 1 intervention
Group B: pentoxifylline 400 mgExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Pregnancy
Beta-Human Chorionic Gonadotropin (β-hCG) was positive
Time frame
1 monthSponsors and contacts
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Source ClinicalTrials.gov