To be effective, organized colorectal cancer screening requires good adherence to diagnostic colonoscopy in the event of a positive test. In France, the rate of diagnostic colonoscopy following a positive colorectal cancer screening test is less than 85%, and the median delay is close to 90 days. After receiving their positive result from the laboratory, individuals with no known follow-up are contacted only six months later by the Regional Cancer Screening Coordination Centers (CRCDC) responsible for following up with individuals who have tested positive. To optimize follow-up with colonoscopy, earlier contact and information about colonoscopy appear to be necessary. The contribution of the general practitioner identified on the test could be an additional lever.
The SUIVICOLO study aims to evaluate the effectiveness on the rate of colonoscopies performed at 6 months of two strategies for optimizing the follow-up of positive results in comparison with control group C (current procedures of the CRCDC Centre Val de Loire without early letter).
The two strategies evaluated will be:
* Group B1: Sending an early letter signed by the CRCDC accompanied by information leaflet about colonoscopy * Group B2: Sending an early letter co-signed by the CRCDC and the general practitioner (identified or provided by the patient on the test identification form) accompanied by information leaflet about colonoscopy.
These strategies will be compared to the current follow-up strategy in a three arm randomized controlled arm.
Aged between 50 and 75 at the time of the positive colorectal cancer screening test
Residing in one of the departments of the Centre Val de Loire region
Date on which the positive CRC screening test result was sent to the beneficiary recorded
Colorectal cancer screening test results sent to the beneficiary within 30 days of the test being read
Subjects who have notified their refusal to allow their data to be used for research purposes will be excluded from the analyses.
Parallel
Usual care follow-up by CRCDC
Other intervention1. 6 months after positive test result: 1st reminder letter from the CRCDC if it has no information about a colonoscopy being performed 2. 12 months after positive test result: 2nd reminder letter from the CRCDC if it has no information about a colonoscopy being performed 3. 18 months after positive test result: 3rd reminder letter from the CRCDC if it has no information about a colonoscopy being performed
Information leaflet about colonoscopy follow-up
Other interventionAn information leaflet about colonoscopy follow-up will be sent in an early letter 7 days after positive test result, and though QR-codes in subsequent reminders.
Endorsement of CRCDC letters from the GP
Other interventionExplicit mention of their general practitioner in letters and reminders sent by the CRCDC to individuals who have tested positive for colorectal cancer, including the information leaflet about colonoscopy or a link to this document (QR code).
Colonoscopy rate at 6 months after a positive test
Percentage of general practitioners who agreed to participate in the project
Colonoscopy rates at 12 months after a positive test
Colonoscopy rates at 18 months after a positive test
Colonoscopy rates at 24 months after a positive test
Click on the lead sponsor to view all of their trials.
University Hospital, Caen
Lead sponsor
Centre Regional de Coordination des Depistages des Cancer - Pays de la Loire
Collaborator
INSERM U1086 ANTICIPE - Université Caen Normandie
Collaborator
URPS Centre Val de Loire
Collaborator
