Health TrialsbyHealthPanel

Heparin vs Placebo for Cardiac Catheterization

ConditionCardiac Disease
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

About this trial

Patients undergoing cardiac catheterization will be randomized to 3 groups: no anticoagulant, low dose anticoagulant and high dose anticoagulant.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

diagnostic cardiac catheterization; Small size sheath; patency of the ulno-palmar circulation

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Heparin

    Drug

    two doses of heparin

  • Placebos

    Drug

    placebo

Treatment groups

1,623 Participants
are divided into 3 treatment groups
Group A: Low dose heparinActive comparator 1 intervention
Group B: High dose heparinActive comparator 1 intervention
Group C: PlaceboPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

radial artery occlusion

by ultrasound

Time frame
1 hour

Secondary outcomes

1

Hematoma> 5 cm

Hematoma at access site

Time frame
one hour post procedure
2

access site bleeding

any bleeding

Time frame
1 hour
3

non access site bleeding

bleeding not related to access site, such as gastrointestinal

Time frame
1 day
4

access site complications

pseudoaneurysm, arteriovenous fistula

Time frame
1 day

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Lead sponsor

Source ClinicalTrials.gov
Apply now