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Influence of Superficial Parasternal Intercostal Plane Block on Internal Thoracic Artery Caliber to Facilitate Surgical Harvesting in CABG

ConditionsPain ManagementParasternal BlockCABG Graft Integrity
Trial statusNot yet recruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age22-65
SponsorAin Shams University

About this trial

Influence of Superficial Parasternal Intercostal Plane Block (SPIPB) on Internal Thoracic Artery (ITA) Caliber and Surgical Harvesting Efficiency in Coronary Artery Bypass Grafting (CABG)

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

• Age group: Adult patients from age of 22 to 65 years.

Sex: Both sexes

Patients undergoing CABG with IMA harvesting

Disqualifiers

• Patients with pre-existing active bloodstream infection or systemic infection

Refuse consent

IMA graft not suitable

Morbidly obese (BMI > 40 )

Trial design

Design model

Parallel

Treatments tested in this trial

  • Bupivacaine

    Drug

    Superficial parasternal block will be given to assess diameter of IMA by using US to assess caliber and ease of harvesting.

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: Bupivacaine groupActive comparator 1 intervention
Group B: Control groupNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Change in Internal Thoracic Artery (ITA) Diameter

Change in the diameter of the Internal Thoracic Artery (ITA) measured in millimeters (mm) after SPIPB administration.

Time frame
Measured 15 minutes after the SPIPB injection by intraoperative ultrasound.
2

Change in Internal Thoracic Artery (ITA) Cross-Sectional Area

Change in the cross-sectional area of the Internal Thoracic Artery (ITA) measured in square millimeters (mm²) after SPIPB administration.

Time frame
Measured 15 minutes after the SPIPB injection by Intraoperative ultrasound.

Secondary outcomes

1

Time Required for ITA Harvesting

Total time in minutes (min) required to harvest the Internal Thoracic Artery.

Time frame
Measured during the surgical harvesting procedure.
2

Technical Difficulty of ITA Harvesting

Assessed using a Technical Difficulty Scale. The scale ranges from 1 (Very Easy) to 5 (Very Difficult), where a higher score indicates a worse outcome (more difficult harvesting).

Time frame
Assessed by the surgeon immediately after the harvesting procedure.
3

Postoperative Pain Score

Postoperative pain assessed using the Visual Analog Scale (VAS) for pain. The scale ranges from 0 mm (No Pain) to 100 mm (Worst Possible Pain), where a higher score indicates a worse outcome.

Time frame
Measured at 24 hours postoperatively.
4

Postoperative Opioid Consumption

Total postoperative opioid consumption, measured in Morphine Milligram Equivalents (MME).

Time frame
Measured over the first 24 hours postoperatively.

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Ain Shams University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: