Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age50-90
SponsorHoffmann-La Roche

About this trial

This study is a pre-screening process used to assess participants' potential eligibility for Roche interventional Alzheimer's disease studies.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Ability and willingness to participate in an interventional clinical study, including meeting key eligibility criteria of linked interventional Roche AD studies (e.g., specific age ranges)

Ability and willingness to receive information about potential eligibility in an associated interventional Roche AD study

Disqualifiers

Dependency in basic activities of daily living (bADLs) due to cognitive impairment

Visual or auditory impairment that would prevent them from performing the cognitive assessments (eyeglasses and hearing aids are permitted)

Any self-reported evidence or known diagnosis of a neurological or neurodegenerative condition that may lead to cognitive impairment other than AD

History of severe, clinically significant central nervous system trauma

Trial design

Design model

Single group

Treatments tested in this trial

  • No Intervention

    Other intervention

    Participants will have their blood drawn and cognitive score measured by the ISLT.

Treatment groups

80,000 Participants
are divided into 1 treatment group
Group A: Screening ArmOther 1 intervention

Trial outcomes

Primary outcomes

1

Concentration of pTau217 in Blood on Day1

Time frame
Day 1
2

Cognitive score in ISLT on Day 1

Time frame
Day 1

Secondary outcomes

Other outcomes

Sponsors and contacts

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