Statins and ARBs on Rheumatoid Activity

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18-65
SponsorSherief Abd-Elsalam

About this trial

Investigational and comparative study between the anti-inflammatory effectof both angiotensin reeptor blockers and statins on rheumatoid arthritis disease activity on Egyptian patients

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Rheumatoid arthritis.

Disqualifiers

Pregnant or lactating

Hepatic or renal impairment.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Angiotensin receptor blockers

    Drug

    Candesartan

  • Statins

    Drug

    Atorvastatin

Treatment groups

45 Participants
are divided into 3 treatment groups
Group A: Control groupNo intervention 0 interventions
Group B: Angiotensin receptor blockersActive comparator 1 intervention
Group C: StatinsActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Change in disease activity score

DAS28-ESR

Time frame
6 months

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Sherief Abd-Elsalam

Lead sponsor

Tanta University

Sponsor institution