The bacterial sexually transmitted infections (STIs) chlamydia, gonorrhea, and syphilis cause multiple adverse outcomes in women, and prevention strategies are critically needed. This project will determine the efficacy of doxycycline post-exposure prophylaxis (doxy PEP) to prevent STIs among women through a phase IV, open-label, randomized controlled trial.
Female
Aged 18-35
diagnosis of CT, gonorrhea, syphilis, or trichomonas in the past year
reporting 2 or more sexual partners in the past 6 months
Pregnant, nursing, or intending to become pregnant
Reported allergy to tetracyclines
Liver disease or end-stage renal disease
Non-English Speaking
Tulane University
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator
University of Alabama at Birmingham
Collaborator
Louisiana State University Health Sciences Center in New Orleans
Collaborator