About this trial
This study aims to evaluate whether the use of alpha-blockers before flexible ureterorenolithotripsy facilitates the passage of the ureteral access sheath. The trial will enroll adult patients diagnosed with kidney stones who are scheduled for flexible ureteroscopy. Participants will be randomly assigned to receive or not receive alpha-blockers for seven days before surgery. The primary outcome is the rate of successful sheath placement without the need for a second procedure. Secondary outcomes include the incidence of ureteral injuries and the need for additional surgical interventions. The goal is to improve surgical efficiency and patient outcomes in the treatment of kidney stones.
Eligibility criteria
Qualifiers
Age ≥ 18 years
Diagnosis of nephrolithiasis with surgical indication for flexible ureterorenolithotripsy
Ability to provide written informed consent
Disqualifiers
Age < 18 years
Pregnancy
History of ureteral stricture, prior ureteral reconstructive surgery, and/or abdominal or pelvic radiotherapy
Prior ureteroscopy or ipsilateral double-J stent placement within the past 3 months
Trial design
Treatments tested in this trial
- Experimental: Alpha-blocker group
- No intervention (observational study)
Treatment groups
Sponsors and collaborators
Pedro de Figueiredo Buchalla
Lead sponsor
Centro Universitário FMABC
Sponsor institution