Health TrialsbyHealthPanel

Antibiotic Prophylaxis in Patients Undergoing GVO

ConditionsGastric VarixSepsisLiver CirrhosesFever
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age20-85
SponsorTaipei Veterans General Hospital, Taiwan

About this trial

We design a randomized trial to clarify the necessity of antibiotic prophylaxis for the patients chronic liver disease with gastric varices treated by elective GVO.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with live cirrhosis and/or hepatoma

Aged 20 to 85, who had endoscopy-treatment EV(-)GV(+)or EV<GV

Disqualifiers

Had a terminal illness of any major organ system,such as heart failure, kindey failure,COPD

Patients recieve antibiotics recently.

Patients suspected infection.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Ertapenem

    Drug

    inject from iv drip before endoscopic cyanoacrylateinjection obliteration

Treatment groups

150 Participants
are divided into 2 treatment groups
Group A: AntibioticExperimental treatment 1 intervention
Group B: ControlNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Prevetion of sepsis

If Antibiotic Prophylaxis can reduce sepsis in Patients Undergoing GVO

Time frame
3 years

Secondary outcomes

1

Rebleeding rate

If Antibiotic Prophylaxis can reduce GV rebleeding rate

Time frame
3 years
2

Pevention of Refractory bacterial infection

If Antibiotic Prophylaxis can reduce infection rate in Patients Undergoing GVO

Time frame
3 years
3

Mortality

If Antibiotic Prophylaxis can decrease mortality in Patients Undergoing GVO

Time frame
3 years

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Taipei Veterans General Hospital, Taiwan

Lead sponsor

Source ClinicalTrials.gov
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