About this trial
The study will evaluate whether atropine eyedrops are beneficial when used after certain eye surgeries.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
patient undergoing vitrectomy surgery
able to give informed consent
Disqualifiers
post-operative eyedrop regimens that include topical non steroidal anti-inflammatory medications
subjects with altered post-operative eyedrop schedule for enhanced inflammation control
documented allergy to atropine
Trial design
Parallel
Treatments tested in this trial
Atropine 1%
DrugSubtraction of atropine eyedrops from post-operative treatment regimen
Treatment groups
Trial outcomes
Primary outcomes
Pain score on the Visual Analog Scale (VAS)
Whether atropine use impacts post-operative pain score on the standard Visual Analog Scale (VAS)
Secondary outcomes
Anterior chamber inflammation (aqueous cell and flare)
Whether atropine impacts the occurrence of post-operative inflammation, quantified as aqueous cell and flare, using the Standardization of Uveitis Nomenclature (SUN) Criteria
Cystoid macular edema detected by optical coherence tomography
Whether atropine impacts the occurrence of cystoid macular edema after surgery, detected by optical coherence tomography scanning of the retina
Time to visual recovery
Whether atropine impacts the time to visual recovery
Intraocular pressure
Whether atropine impacts intraocular pressure after surgery
Sponsors and contacts
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