About this trial
The goal of this clinical trial is to learn if there is a difference in morphine requirements in patients after upper extremity surgeries including shoulder arthroscopy. The main question it aims to answer is whether there is a difference between Interscalene brachial plexus blocks with the addition of buprenorphine, dexamethasone, and clonidine and the same block without the adjuvant.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients ≥ 18 years old
Patients undergoing shoulder arthroscopy
Patients willing to participate and sign informed consent
Disqualifiers
Severe COPD/other contraindication to general anesthesia
Patient with a weight of less than 60 kg
Dementia, not alert or oriented to person, place, or time
Chronic pain patient with daily opioid use at home.
Trial design
Parallel
Treatments tested in this trial
Interscalene block with the addition of buprenorphine, clonidine, dexamethasone
DrugAddition of the adjuvant buprenorphine, dexamethasone, and clonidine in the nerve block performed prior to shoulder arthroscopy surgery
Interscalene block with buprenorphine alone
DrugAddition of the adjuvant buprenorphine alone the in nerve block performed prior to shoulder arthroscopy surgery
Treatment groups
Trial outcomes
Primary outcomes
Morphine requirement post surgery
To compare the morphine equivalents administered in the first 24 hours after arrival in the recovery area between the two groups.
Secondary outcomes
Pain reported via a numeric rating scale (NRS)
To measure pain via a numeric rating scale (NRS) immediately after arrival to recovery area from surgery (time: 0hr), and again at 2, 24, and 48 hours.
Sponsors and contacts
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