CAPITAL OFFLOAD-SHOCK
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorOttawa Heart Institute Research Corporation
About this trial
CAPITAL OFFLOAD-SHOCK will aim to answer if early use of renal replacement therapy, like dialysis, in patients with reduced body fluids causing the heart to be unable to pump enough blood through the body reduces in-hospital death when compared to the current standard of care. The current standard of care is to wait until renal replacement therapy is clinically necessary.
Eligibility criteria
Qualifiers
adult patients >/= 18 years of age admitted to an intensive care unit
Diagnosed clinically with Society for Cardiovascular Angiography and Interventions (SCAI) Class C or D cardiogenic shock
Clinical or hemodynamic evidence of volume overload
Disqualifiers
Patients whose care plan, as determined by the treating clinical team, will not include renal replacement therapy
Decision has already been made by the treating clinical team to initiate renal replacement therapy
Hyperkalemia with serum potassium >/= 6mmol/L at the time of screening
Severe metabolic acidosis with serum bicarbonate </= 12 mmol/L at the time of screening
Trial design
Treatments tested in this trial
- Immediate renal replacement therapy
Treatment groups
456 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov