To assess the effect of intraoperative transversus abdominis plane (TAP) blocks on the amount of opioid pain medications expressed as morphine milliequivalents (MME) used postoperatively in patients who have undergone cesarean delivery (CD) in the setting of complex obstetric surgery (COS).
Prior exploratory laparotomy
History of non-obstetric open intra-abdominal surgery
History of three or more prior cesarean deliveries
History of intra-abdominal or pelvic adhesive disease
Received general anesthesia
History of less than 3 cesarean deliveries if do not meet other inclusion criteria
History of chronic opioid use
History of substance abuse (i.e. alcohol, methamphetamine/amphetamine, abuse of prescription opioid medication, or heroin use)
Parallel
Bupivicaine intervention arm
DrugTAP blocks in intervention group will include 0.5% bupivacaine in 30mL solution of 15mL normal saline and 15mL bupivacaine
Placebo arm
DrugPlacebo group TAP block syringe will include 30mL normal saline
Pain medication requested
Total pain medication requested expressed in morphine milligram equivalents.
Total MME requested within first 24 hours postoperatively
Total MME requested within 48 hours postoperatively
Total MME at one week after surgery
Functional assessment of activities of daily life (ADL) at one week postoperatively
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University of Tennessee
Lead sponsor
Regional One Health
Collaborator
