Comparing the Efficacy of Propofol and Dexmedetomidine in Prevention of Emergence Agitation After Sevoflurane Anesthesia in Children

ConditionEmergence Delirium, Anesthesia

Trial statusRecruiting

Trial phasePhase 4

Trial typeInterventional

Biological sexAll

Age2-12

SponsorPakistan Institute of Medical Sciences

About this trial

This is a clinical study for comparing the efficacy of two drugs i.e propofol and dexmedetomidine in prevention of a group of post operative abnormal behaviours that can occur after sevoflurane anesthesia in children and we will measure this by a special scale which is used to evaluate these behavioural changes.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

congenital anomalies

allergic to study medications

chronic pain syndromes

malnourishment -

Trial design

Design model

Parallel

Treatments tested in this trial

propofol 1mg/kg
Drug
1mg/kg propofol given 10 minutes before the end of surgery
Dexmedetomidine
Drug
0.3mcg/kg of dexmedetomidine to group D patients will be given after dilution with 10ml of 0.9%saline over 1 min given 10 minutes before extubation

Treatment groups

114 Participants

are divided into 2 treatment groups

Group A: Group propofolActive comparator 1 intervention

Group B: group dexmedetomidineActive comparator 1 intervention

Trial outcomes

Primary outcomes

Emergence Delirium PAED score

Time frame

PAED score will be calculated upon arrival in Post Anesthesia care unit then at 5,10,15,30 minutes interval

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Pakistan Institute of Medical Sciences

Lead sponsor

Source ClinicalTrials.gov

Apply now