About this trial
This study compares the incidence of pruritus (itching) requiring treatment between two doses of intrathecal morphine (0.1 mg vs 0.2 mg) when used for spinal anesthesia during cesarean section. The study aims to determine if the lower dose (0.1 mg) can reduce pruritus incidence while maintaining adequate pain relief.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Full-term pregnancy
Scheduled for non-emergency cesarean section
ASA physical status I-III
Non-complicated pregnancy
Disqualifiers
Contraindication to spinal anesthesia or study drugs
Refusal to participate in the study
BMI ≥ 40 kg/m²
History of systemic skin disease or current itchy skin condition
Trial design
Parallel
Treatments tested in this trial
Morphine Sulfate
Drugintrathecal administered morphine
Treatment groups
Trial outcomes
Primary outcomes
Incidence of pruritus requiring treatment [Time Frame: 24 hours post-operatively]
* Percentage of participants requiring treatment for pruritus within 24 hours after spinal anesthesia * Measured using numerical rating scale (0-10), with treatment indicated for score ≥4 * Percentage of participants requiring treatment for pruritus within 24 hours after spinal anesthesia * Measured using numerical rating scale (0-10), with treatment indicated for score ≥4 * Percentage of participants requiring treatment for pruritus within 24 hours after spinal anesthesia * Measured using numerical rating scale (0-10), with treatment indicated for score ≥4
Sponsors and contacts
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