After an initial period of standard treatment, they received further care aimed at helping the surface of the eye heal. Clear instructions were given on how to use and store the treatment properly. Patients were then monitored regularly over several months, with doctors checking their healing progress during follow-up visits. The study continued for a total of 24 weeks to observe how well and how quickly the eye surface recovered.
Corneal epithelial defects for more than 2 weeks no improvement using standard treatment
• Systemic conditions e.g. uncontrolled Diabetes, autoimmune disorders
Recent eye surgery within last 3 months
Hereditary corneal dystrophies
Active eye infections
Parallel
Topical insulin eye drops
DrugTopical Insulin eye drops will be administered every 6 hours till healing of corneal epithelial defects
Amniotic Membrane Graft
Procedure/SurgerySurgically amniotic membrane grafts will be applied to bridge and heal the corneal defects
Cure rate
This will be the number of patients out of total number in each group completely cured of corneal epithelial defects
Mean time to healing
This will be the mean time to complete healing in weeks from initiation of treatment until full epithelial closure as confirmed by lack of fluorescein staining on slit-lamp examination.
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