About this trial
Cesarean section is one of the commonly performed surgical procedures in the world. Once baby is delivered during the surgical procedure anesthesiologist administer Oxytocin drug through IV cannula which helps the Uterus to contract so that excessive blood loss doesnt occur. But this is associated with fall in blood pressure frequently requiring administration of medications to treat low blood pressure. The most frequently used drug is phenylephrine which can administered along with oxytocin to prevent fall in blood pressure. This study will compare to different doses of Phenylephrine to prevent fall in blood pressure.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
Patients having a placental abnormality
Patients taking beta-blocker and vasodilator therapy
Patients with hypertensive disorder
Trial design
Parallel
Treatments tested in this trial
Phenylephrine bolus 75 micrograms
DrugAfter delivery of Baby during C section, patient will be administered 3 IU of Oxytocin over 3 minutes along with 75 micrograms of Phenylephrine Intravenously.
Phenylephrine bolus 50 micrograms
DrugAfter delivery of Baby during C section, patient will be administered 3 IU of Oxytocin over 3 minutes along with 50 micrograms of Phenylephrine Intravenously.
Treatment groups
Trial outcomes
Primary outcomes
Number of Hypotensive episodes
Hypotension will be defined as fall in Mean Arterial pressure by more than 20% from baseline value.
Secondary outcomes
Rescue Phenylephrine consumed
Sponsors and contacts
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