Comparison of Two Treatment Regimens of Helicobacter Pylori Infection
ConditionHelicobacter Pylori Infection
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age12-90
SponsorRehman Medical Institute - RMI
About this trial
The goal of this interventional study is to compare the efficacy of clarithromycin Vs levofloxacin based regimen in treatment of Helicobacter pylori infection in patients presenting to medical OPD who are tested positive for H pylori infection.. The main question\[s\] it aims to answer are:
• Which regimen is superior in terms of efficacy Participants will be treated for H pylori Infection in with two different regimen If there is a comparison group: Researchers will compare two groups Group 1 will receive clarithromycin based regimen group 2 will receive levofloxacin based regimen to see the treatment response.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
All patients who tested positive on stool antigen will be included.
Disqualifiers
patients under 12 years old. Patients who have penicillin allergy.
Patients who have underlying dysrhythmia forbidding the use of macrolide.
Patient who have hypersensitivity to any of these antibiotics.
Trial design
Design model
Parallel
Treatments tested in this trial
Clarithromycin
DrugDrug regimens will be given for 14 days, and omeprazole for 6weeks
Levofloxacin
DrugDrug regimens will be given for 14 days, and omeprazole for 6weeks
Treatment groups
156 Participants
are divided into 2 treatment groupsGroup A: Regime 1Active comparator 1 intervention
Group B: Regime 2Active comparator 1 intervention
Trial outcomes
Primary outcomes
1
Treatment of H pylori infection
Treatment of H pylori infection documented by negative stool antigen
Time frame
2weeks after completion of treatment regimenLocations
Sponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: