Dual Trigger With HCG and GnRH Agonist on Thawed Modified Natural Cycle Embryo Transfer

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age25-44
SponsorNational Taiwan University Hospital

About this trial

Impact of dual trigger using recombinant human chorionic gonadotropin (HCG) and gonadotropin-releasing hormone (GnRH) agonist on thawed modified natural cycle outcomes: an open-label multi-center randomized controlled trial.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • GnRH agonist

    Drug

    GnRH agonist add to hcg for trigger

Treatment groups

170 Participants
are divided into 2 treatment groups
Group A: dualExperimental treatment 1 intervention
Group B: hcgNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Implantation

Implantation is defined as a positive serum β-hCG (\>20 mIU/mL) measured 14 days after embryo transfer.

Time frame
14 days after embryo transfer

Secondary outcomes

1

Clinical pregnancy

Clinical pregnancy is defined as visualization of a gestational sac on transvaginal ultrasonography one week after pregnancy has been confirmed.

Time frame
one week after confirm pregnancy
2

Ongoing pregnancy rate

An ongoing pregnancy is defined as a viable intrauterine pregnancy with fetal cardiac activity at ≥9 weeks' gestational age.

Time frame
5 weeks after confirmed pregnancy
3

Miscarriage rate

Time frame
before delivery
4

Gestational age (weeks) at delivery

Gestational age (weeks) at delivery

Time frame
delivery

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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