About this trial
As baby grows inside the womb of mother, heart and other organs develop. The heart activity can be recorded by placing a transducer on the belly of mother. The tracing obtain provides information about heart rate, any increase or decrease in heart rate and how much it varies with time. Variation in heart rate along with increase is indicator of fetal well being. Some mothers are at high risk of pre-term birth that is baby delivery before 37 weeks of gestation. In such cases steroids are given to mother to accelerate lung development of the baby so that it can easily adapt to outside world. Dexamethasone and Betamethasone are commonly used steroids which can also effect fetal heart activity.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
History of pre term labor
Preterm pre labor rupture of membranes
Third trimester bleeding due to placenta previa
Disqualifiers
IUGR
Uteroplacental insufficiency
Oligohydroamnios
Maternal drug therapy that can effect fetal heart rate
Trial design
Parallel
Treatments tested in this trial
Betamethason Sodium Phosphate
DrugIntramuscular injection of Betamethasone 12mg will be administered on 2 consecutive days
Dexamethasone
Drugtwo doses of 12mg of IM Dexamethasone given 24 hours apart
Treatment groups
Trial outcomes
Primary outcomes
Mean number of accelerations on fetal cardiotocography
Long term heart rate variability on fetal cardiotocography
Sponsors and contacts
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Rawalpindi Medical College
Lead sponsor
Rawalpindi Medical College, Pakistan
Collaborator